Calcium Kidney Stones

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Calcium Kidney Stones

Copyright © 2010 Massachusetts Medical Society. A 43-year-old man presents for evaluation of recurrent kidney stones. He passed his first stone 9 years earlier and has had two additional symptomatic stones. Analysis of the first and the last stones showed that they contained 80% calcium oxalate and 20% calcium phosphate. Analysis of a 24-hour urine collection while the patient was not receiving...

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Association of Polymorphism at 3׳-UTR of Urokinase Gene with Risk of Calcium Kidney Stones

Urokinase might play a role in the formation of kidney stones. This study was done to determine the association between +4065 T/C polymorphism at the 3′-untranslated region of urokinase gene and calcium kidney stones. This Case-Control study was carried out on 70 cases with a history of calcium kidney stones and 70 controls from the Baqiyatallah hospital of Tehran in 2013. The study of polymorp...

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Dietary Zinc and Incident Calcium Kidney Stones in Adolescence.

PURPOSE We determined the association between dietary zinc intake and incident calcium kidney stones in adolescents. We also examined the relationship between dietary zinc intake and urinary zinc excretion between cases and controls. MATERIALS AND METHODS We conducted a nested case-control study within a large pediatric health care system. Three 24-hour dietary recalls and spot urine chemistr...

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Diversity in Protein Profiles of Individual Calcium Oxalate Kidney Stones

Calcium oxalate kidney stones contain low amounts of proteins, some of which have been implicated in progression or prevention of kidney stone formation. To gain insights into the pathophysiology of urolithiasis, we have characterized protein components of calcium oxalate kidney stones by proteomic approaches. Proteins extracted from kidney stones showed highly heterogeneous migration patterns ...

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Pathophysiology-based treatment of idiopathic calcium kidney stones.

Idiopathic calcium oxalate (CaOx) stone-formers (ICSFs) differ from patients who make idiopathic calcium phosphate (CaP) stones (IPSFs). ICSFs, but not IPSFs, form their stones as overgrowths on interstitial apatite plaque; the amount of plaque covering papillary surface is positively correlated with urine calcium excretion and inversely with urine volume. The amount of plaque predicts the numb...

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ژورنال

عنوان ژورنال: New England Journal of Medicine

سال: 2010

ISSN: 0028-4793,1533-4406

DOI: 10.1056/nejmcp1001011